The Results are In!
Our latest study results which detail the sensitivity of our Cardio quickPredictTM assay have just been published online February, 2020 (ahead of print) in Toxicological Sciences. The results show that our assay identified structural and electrophysiological cardiotoxic effects for a large number of already well-characterized drugs. The data shows that our compound / drug screening test could provide drug developers with an early, more comprehensive evaluation of cardiovascular toxicity.
A Targeted Metabolomics-Based Assay Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Identifies Structural and Functional Cardiotoxicity Potential
“This is the first large-scale, metabolomics-based study evaluating both structural and electrophysiological cardiotoxic effects for drugs,” said Jessica Palmer, M.S., associate director of toxicology at Stemina and author on the paper. “With its ability to produce a ‘metabolic footprint’ of the cardiomyocyte secretome, Cardio quickPredictTM could be used as either a standalone assay or in combination with other tests to help investigators with lead identification or optimization.”