In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Valproic Acid Analogues [ASCCT, 2020]

Presented by Jessica Palmer at the American Society for Cellular and Computational Toxicology; October, 2020

Previous work showed that the potency ranking from devTOXqP assay was consistent with in vivo developmental toxicity potency, but whether the assay could quantitatively predict in vivo exposure exerting developmental toxicity was unknown.