A Human Induced Pluripotent Stem Cell-Based In Vitro Assay Predicts Developmental Toxicity Through a Retinoic Acid Receptor-Mediated Pathway for a Series of Related Retinoid Analogues [Reproductive Toxicology, 2017]

The relative developmental toxicity potency of a series of retinoid analogues was evaluated using a human induced pluripotent stem (iPS) cell assay that measures changes in the biomarkers ornithine and cystine.

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