Developmental Toxicity Testing of Gaseous Chemicals with a Human Pluripotent Stem Cell-Based Assay [Teratology Society 2019]

Presented at the Teratology Society Annual Meeting in San Diego, California; June 2019

Innovative in vitro toxicity screening assays aimed at reducing or replacing the use of animals in chemical safety testing are critical to meet the safety requirements across industries. Multiple publications have demonstrated the applicability of various in vitro assays for evaluating the developmental toxicity potential of non-volatile chemicals; however, very little information is available regarding application of these assays to volatile chemicals (e.g., gases).